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Vardenafil drug information
What is Vardenafil?
Vardenafil is the generic name for brand-name drug Levitra. It gained attention as the second drug to be approved by the FDA for treating erectile dysfunction (Sildenafil, better known as Viagra, was the first). In addition to this indication, Vardenafil may also be effective in treating premature ejaculation. Since it gained approval in 2003, Vardenafil has been used by millions of patients worldwide.
How Does Vardenafil Work?
Vardenafil is a type of drug called a PDE5 inhibitor. The way that it works is hindering the effects of a certain enzyme which is called phosphodiesterase type 5 (or PDE5) which normally causes muscle constriction in the penis. By inhibiting PDE5, the penile muscles are more relaxed and more blood flows into the spongy tissues. This causes erections to last for longer and increases penis stiffness. Vardenafil only enhances erections. It will not cause an erection to occur without sexual stimulation.
Vardenafil vs. Sildenafil
Vardenafil and Sildenafil (better known by its brand name of Viagra) are very similar in many ways. They are both PDE5 inhibitors and share the same basic mechanism of action. They both also produce the same side effects and carry the same precautions. However, there are a few important differences between Vardenafil and Sildenafil. Firstly, Vardenafil has a half life of 4-5 hours compared to 3-4 hours in Sildenafil. This means that the effects of Vardenafil are longer lasting. Vardenafil also is slightly different structurally to Sildenafil. Because of this, Vardenafil may be effective in treating erectile dysfunction in men with whom Sildenafil was not effective. There is also evidence that the effects of Vardenafil may occur faster. Lastly, Vardenafil is usually cheaper to purchase than Sildenafil.
How to take Vardenafil
Vardenafil should only be taken exactly as directed by a doctor. Typically, Vardenafil is taken in dosage amounts of 10 mg about 1 hour before anticipated sexual activity. Elderly patients should have treatment initiated in dosages of 5 mg. Patients with certain health conditions or taking other medicines may also require a lower initial dosage. Vardenafil dosage may be reduced or increased as needed to a range of 5-20 mg. Not more than 20 mg of Vardenafil should be taken in a period of 24 hours. You may take Vardenafil without regards to food or meals.
Common Side Effects from Vardenafil
It is common for patients to experience some mild side effects from Vardenafil which are usually not serious. They may include: head or neck pain, nasal congestion, dyspepsia, acid reflux, running nose, vertigo, or feeling nauseous. You may also experience a change in the way that you perceive light including blurred eyesight or changes to colors. Inform your doctor if any of these adverse effects are bothersome or continue.
Potential Serious Side Effects from Vardenafil
The vast majority of patients taking Vardenafil do not have any serious adverse effects. However, in rare cases, Vardenafil may cause sudden blindness. Vardenafil can also cause prolonged or painful erections that may lead to lasting erectile damage. Immediately get medical attention if these conditions occur. If you experience these side effects while taking Vardenafil, contact your health care professional at once: changes to heart rate, convulsions, changes to how you hear, or forgetfulness. Engaging in sexual activities can cause physical exertion and strain the cardiovascular system. This strain may be worsened by Vardenafil. If you have any of these side effects during sexual activities while taking Vardenafil, you should immediately stop all activity and get medical attention: becoming very dizzy, loss of conscious, or pains in chest.
Vardenafil Contraindications
Males with certain health factors may not be able to take Vardenafil safely or may need to have treatment initiated at lower initial dosages. It is vital that you inform your doctor of your complete health history before using Vardenafil, especially of these conditions which may be contraindicated for the medicine: allergies, penile disorders (including scarred or angled penis), anemia, impaired kidneys, hepatic impairment, blood-related disorders or cancers, cardiovascular problems, active ulcer, recently had a stroke, hypertension, or hypotension. Vardenafil should not be taken by children and is not meant for use in women. Elderly patients should use caution when taking Vardenafil as they are more likely to experience adverse effects.
Precautions about Vardenafil
Caution should be used the first few times that patients use Vardenafil or anytime that their dosage is increased. Patients should be on the lookout for adverse effects. As Vardenafil may cause dizziness or vision changes, do not perform potentially dangerous activities like driving until you are certain you can do so safely. Be cautious not to have accidents from falling.
Interactions with Vardenafil
Vardenafil should never be taken with nitrate drugs which may include: angina medicine, the recreational drugs "poppers", or medicine for congestive heart failure, amongst others. A severe interaction could take place if Vardenafil is used with these drugs. An interaction could also occur if Vardenafil is taken with other drugs so inform your doctor of all medicines, drugs and natural treatments you use, particularly of: other treatments for erectile dysfunction, alpha blockers, antibiotics, anticonvulsants, or hypertension medicine.