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Tramadol/Acetaminophen drug information
Tramadol/Acetaminophen Description and Indications
Tramadol/Acetaminophen is a formulation of two generic pain killers. This formulation is often called by its brand name of Ultracet though it is available from many manufacturers. Tramadol/Acetaminophen is approved for treating acute pains on a short-term basis of no longer than 5 days.
Tramadol/Acetaminophen Drug Synergy
Both Tramadol and Acetaminophen are pain killers. The former is a type of opiate which is synthetically derived from codeine. The later is a popularly-used over-the-counter pain killer which also has fever-reducing properties. When these two drugs are formulated together, it creates a drug synergy in which the pain-killing benefits of each drug are enhanced. This drug synergy does not, however, enhance the opiate qualities of Tramadol which can include euphoria or sedation. As Acetaminophen will cause severe liver damage in large dosage amounts, adding Acetaminophen to Tramadol also deters recreational use of the opiate and prevents patients from developing a high tolerance it.
How to take Tramadol/Acetaminophen
Tramadol/Acetaminophen should only be taken as prescribed by a doctor. Typically, Tramadol/Acetaminophen is taken as 2 tablets every 4-6 hours on an as-needed basis. In the 37.5/325 mg formulation of Tramadol/Acetaminophen, no more than 8 tablets should be taken in a period of 24 hours. Unless otherwise directed, you may take Tramadol/Acetaminophen without regards to meals. This medicine should never be taken for longer than 5 days. If your pain persists, contact your doctor. Note that your dosing instructions for Tramadol/Acetaminophen may be different.
Note about Tramadol/Acetaminophen
No more than 4000 mg of Acetaminophen should be taken in a period of 24 hours. If the user is also consuming alcohol, then no more than 2000 mg of Acetaminophen should be taken. Taking more than this amount of the drug can lead to sever or even fatal liver damage. For this reason, it is especially crucial that Tramadol/Acetaminophen is not abused for its opiate properties.
Adverse Effects from Tramadol/Acetaminophen
It is common for patients to have adverse effects while taking Tramadol/Acetaminophen though these effects are usually not serious. Inform your doctor if any of these effects are continual or deteriorate: feeling nauseous, becoming constipated, feeling lightheaded, dizzy spells, drowsiness, or perspiration. You should notify your doctor at once about these adverse effects from Tramadol/Acetaminophen: unusual moods/behaviors, excruciating abdomen pains, or troubles with urination. Though rarely occurring, immediately get medical help for any of these adverse effects: loss of consciousness, seizures, unusual breathlessness, slowed breathing, severe lethargy, signs of liver damage (darkened urine, chronic nausea, severe abdomen pains, jaundice), symptoms of serotonin syndrome (becoming unusually restless, hallucinating, unsteadiness, rapid pulse, extreme dizziness, unusual fever, muscular twitches), or signs of an allergic reaction.
Tramadol/Acetaminophen Contraindications
Tramadol/Acetaminophen should not be used by everyone, especially patients who have certain health risk factors. Do not take Tramadol/Acetaminophen until you have discussed your complete health history with your doctor. The following are just some of the conditions which may be contraindicated for Tramadol/Acetaminophen: allergies, respiratory problems, brain problems (including injury and tumor), impaired kidneys, hepatic impairment, psychiatric problems, frequent alcohol use, personal/family history of substance abuse, gastro or intestinal problems, urinary problems, planned surgeries, breastfeeding, or pregnancy. Note that your doctor may still prescribe Tramadol/Acetaminophen to you in the presence of any of these conditions but may decide to alter your dosage or monitor you for adverse effects.
Tramadol/Acetaminophen during Pregnancy and Breastfeeding
Only use Tramadol/Acetaminophen during pregnancy if your doctor decides the benefits outweigh the risks. Taking Tramadol/Acetaminophen while pregnant could harm your unborn child or lead to a drug dependency in your infant marked by withdrawal symptoms upon birth. Do not take Tramadol/Acetaminophen while you breastfeed as it can be passed to your child and cause harm.
Precautions while taking Tramadol/Acetaminophen
You should avoid consuming alcoholic beverages and other products containing alcohol during treatment with Tramadol/Acetaminophen. When combined with alcohol, the likelihood of Acetaminophen causing severe liver damage is increased. Do not perform any dangerous tasks while taking Tramadol/Acetaminophen until you are certain that you can do so safely. Patients, particularly the elderly, should be cautious to avoid falling while taking Tramadol/Acetaminophen as the medicine may cause dizziness.
Interactions with Tramadol/Acetaminophen
Do not use Tramadol/Acetaminophen without first telling your doctor of all medicines, drugs, and natural treatments that you may use as a serious interaction could take place. The following are just some of the drugs which may interact with Tramadol/Acetaminophen: monoamine oxidase inhibitors, narcotics, pain killers, psychiatric medicines (including antidepressant and anti-anxiety drugs), MDMA ("X"), lithium, St. John's wort, prescription headache medicine, antiviral drugs, antibiotics, medicine for fungal infections, and anticonvulsants. Avoid consuming alcohol and any substance which could cause drowsiness.
Overdose of Tramadol/Acetaminophen
Taking too much Tramadol/Acetaminophen can lead to a serious and sometimes fatal overdose. Some of the symptoms of overdose on Tramadol/Acetaminophen may include: respiratory depression, sluggish/erratic pulse, coma, fainting, or seizures. Even if there are no symptoms of overdose, immediately get emergency medical treatment if you think that you or someone else has taken too much Tramadol/Acetaminophen. You may also contact your local poison control helpline for advice.