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Leflunomide drug information
Why Leflunomide is taken
Leflunomide is a prescription medicine that works by affecting the patient's immune system and significantly reducing inflammation and pain that may have been caused by arthritis. A precise diagnosis and full health examination are required for the patient to be prescribed Leflunomide, as this medicine is supposed to be taken only by patients who do require this kind of treatment. You will have to ask your doctor if Leflunomide can be taken for some other conditions you have. Make sure you discuss your needs if the way you are going to use Leflunomide is not one of the most common uses for the medicine. There are some health problems you may treat if you use Leflunomide, besides arthritis pain and inflammation. But your doctor will have to take into consideration all your individual factors when making this decision.
Before using Leflunomide
In case you are using steroid or cancer drugs, as well as any other medications likely to reduce the defense mechanism of your body, your doctor needs to know about it before you start Leflunomide treatment. You are also supposed to tell your doctor if there are any other medical issues that you feel like reporting, because they may require a dose adjustment or some other changes. Your doctor will have to know if you have a history of hepatitis, a history of liver disease, any kind of infection, blood cell disorder, a history of tuberculosis, bone marrow disorder, weak immune system or kidney disease.
Taking your Leflunomide dose
Take Leflunomide exactly as your doctor prescribed, making sure you follow the instructions carefully and never miss your regular doses. Leflunomide needs to be taken regularly and for as long as recommended for the patient to benefit. You will have to take Leflunomide at the same time with a full glass of water. Your doctor will need to see you regularly for blood tests and liver tests, to be sure Leflunomide is working well for you. You may also need to take another medicine after you finished Leflunomide treatment, for the traces of this medicine to be eliminated.
In case of taking too much of Leflunomide
Seek emergency medical help if you ever happened to use too much of Leflunomide, especially if you get such overdose symptoms of this medicine as diarrhea, dark urine, stomach pain, easy bruising or bleeding as well as yellowing of the skin or eyes.
What kinds of side effects can Leflunomide cause?
In any cases of serious side effects of Leflunomide you will have to contact your doctor right away reporting any symptoms you noticed. The following side effects are considered serious and always have to be discussed with your doctor as soon as possible: trouble breathing, loss of appetite, chest pain, cough, itching, burning when you urinate, chills, sore throat, white patches in your mouth, body aches, clay-colored stools, easy bleeding, flu symptoms, fever, pain when urinating, nausea, unusual weakness, pale skin, yellowing of the skin or eyes, fever, easy bruising, sores inside your mouth, headache with red skin rash and peeling, dark urine or stomach pain. Every person taking Leflunomide must keep in mind that some mild side effects of Leflunomide are possible in some cases. In most patients, Leflunomide mild side effects mean the body is adjusting to the dose prescribed and may need some more time for it than usual. You do not need to be worried if you develop such mild side effects of Leflunomide as headache, mild stomach pain, runny or stuffy nose, tingling, dizziness, numbness, mild itching, cold symptoms, weight loss, diarrhea, back pain, skin rash or loss of appetite, or any other ones of the kind.
Are Leflunomide drug interactions possible?
You need to remember that such drugs as cyclosporine, methotrexate, sirolimus, etanercept, azathioprine, efalizumab, mycophenolate mofetil, rifampin, leflunomide, basiliximab, cancer medications, cholestyramine or tacrolimus can weaken your immune system and make it more difficult for the body to fight infections. You will have to avoid combining such medications with Leflunomide if possible. Talk to your doctor about other drugs you are using, as many of them can increase the effects of Leflunomide and harm your liver. Therefore, you will have to tell your doctor about any other drugs you are taking that can do that, especially the following ones: meloxicam, acetaminophen, lisinopril, fluconazole, other arthritis medications, nabumetone, erythromycin, ramipril, naproxen, HIV/AIDS medications, benazepril, valproic acid, diclofenac, quinapril, phenytoin, felbamate, ketoconazole, tuberculosis medications, ibuprofen, etodolac, atorvastatin, piroxicam, niacin, simvastatin, indomethacin, carbamazepine, enalapril, dapsone, itraconazole, birth control pills or hormone replacement therapy.
Is pregnancy a contraindication for taking Leflunomide?
You will have to make sure you never start Leflunomide treatment if you are pregnant or breastfeeding. There is a risk Leflunomide will cause very serious birth defects in the baby, no matter what trimester you are on. You will have to let your doctor know if you are already pregnant when getting your prescription or only going to get pregnant. Your health care provider will be able to provide necessary recommendations for your treatment to go as planned and for your baby to stay unharmed. Not only will you need to avoid pregnancy by taking efficient birth control pills recommended by your doctor (or using other contraception methods), you will also have to do a pregnancy test before using Leflunomide and make sure you are not pregnant. It's not recommended to breastfeed while using Leflunomide, because there is a chance Leflunomide may pass into your breast milk, and the health of your baby may also be affected that way.