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Bupropion drug information
When is Bupropion used?
Bupropion is an atypical antidepressant as it acts primarily on the norepinephrine-dopamine reuptake by inhibiting it. This makes it different from the more common SSRI antidepressants. Bupropion also has some advantages over the more typical antidepressants as it does not cause two of the most common side effects that antidepressants cause, namely the weight gain and sexual dysfunction, which makes it one of the most popular antidepressants on the market. It is sometimes used alone in treatment of depression, but it is more commonly used in conjunction with other depressants, mostly SSRI antidepressants. There have also been shown some improvements in patients suffering from social phobia, as well as those who are suffering from anxiety which is comorbid with depression. It does not, however, have any significant effect on panic disorder. Another very important use for Bupropion is in helping with smoking cessation. It acts as a nicotinic acetylcholine receptor antagonist and by doing so; Bupropion reduces the effects of nicotine cravings and also the withdrawal symptoms that are attributed to cessation of smoking. It can also prevent weight gain which is often caused by cessation of smoking. There are some other uses for Bupropion but these are not that common and there is still some research needed before Bupropion starts to be commonly used in such cases. For now, it is mainly used in cases of depression and in smoking cessation.
What should you discuss with your doctor about Bupropion?
There are certain medical conditions that will prevent you from taking Bupropion and you need to tell your doctor if you are suffering from any of them. This is important as taking Bupropion in case you have any of them can be very detrimental for your health. These conditions include seizure disorders like epilepsy for example and anorexia, bulimia or any other eating disorders. You also need to tell your doctor if you have just ceased using sedatives like Valium or alcohol. In addition to this, you need to inform them of any MAOI regimens you have taken recently, as MAOIs can interact with Bupropion and cause life-threatening complications. There may also be need for your regimen to be adjusted and monitored more closely in case you have any heart or kidney diseases, high blood pressure, bipolar disorder, cirrhosis of the liver or any other liver disorders, or if you have a history of seizures, heart attacks, head injury or tumor of the spinal cord or brain.
In case you are carrying, you will need to make sure that your doctor is aware of this fact as the risks of Bupropion causing detrimental effects to the health of your unborn child cannot be ruled out. In case you become pregnant while already using Bupropion, inform your physician about this as well. Bupropion is known to pass into milk and you should never breastfeed while taking Bupropion. Bupropion should also never be given to anyone younger than 18 unless the doctor has specifically advised differently.
How to take Bupropion properly
It is of vital importance that you take as much Bupropion as prescribed and for the duration of your regimen and not more. Your dosage should only be altered by the doctor and they might do this a few times to establish what dosage of the medication is having the best effects. If you are taking Bupropion for depression, you must not use it for smoking cessation as this may lead to an overdose on Bupropion, which may be very dangerous. Also, if you are taking Bupropion to stop smoking, you are allowed to smoke for a week and then you should set a date when you will stop smoking. Once you stop smoking, you might start using nicotine patches or different products, but your doctor will need to know about them. Drinking alcohol with Bupropion may lead to convulsions and you should either stop drinking altogether or at least limit your intake. Also, if you have been taking large amounts of alcohol before you started taking Bupropion, you need to talk to your doctor about this fact as a sudden stop can also have detrimental side effects (convulsions). If you feel that your thinking or reactions have been impaired by the use of Bupropion, make sure you do not drive or do anything dangerous as long as you feel that way.
Bupropion side effects
Less serious side effects of Bupropion include headaches, insomnia, dry mouth, constipation, tremors, dizziness, vomiting, nausea, changes in your weight and appetite, increased sweating and mild itching of the skin. More serious side effects that need be reported include: convulsions, blistering and red skin rash, fever, itching, joint pain, swollen glands, troubles concentrating, confusion, unusual behavior or thoughts, hallucinations.
Drugs that might interact with Bupropion
Anticoagulants, cancer mediations, hypertension medications, heart medications, HIV drugs, antidepressants, antihistamines, asthma medications, certain antibiotics, certain urinary tract medications, diabetes medications, narcotic painkillers, steroids, theophylline, irritable bowel syndrome medications, malaria medications, prolactinoma medications, immunosuppressants, diet pills and stimulants.
Bupropion overdose
You must contact emergency medical services if you overdose on Bupropion. Symptoms of a Bupropion overdose include muscle stiffness, fast, uneven heartbeat, hallucinations, shallow breathing and fainting.